At TCG CREST CARE, we are pleased to announce that our ongoing research entitled, “Transitioning of ethnicity specific Cell Line Data to predict EGFR-TKI response in lung cancer patients with the shallow learning model approach,” has been accepted for presentation at AI x BIO Conference at Wellcome Genome Campus, UK, between 23rd– 25th June 2025! Sonali Das, CARE, TCG CREST, will be presenting at the conference.
Our study seeks to develop an AI/ML-based model to predict EGFR-TKI response in NSCLC across different ethnic backgrounds. A major challenge remains the limited availability of structured patient datasets, which hinders deeper investigation. Drug response patterns in Caucasian patients closely matched those in cell lines of the same origin, unlike East Asian-derived models, highlighting an ethnicity-specific mutation landscape captured in cell system supporting their potential use as reliable surrogates in pre-clinical studies.
We look forward to connecting!
