Chandan Guha

Scientific Advisor, CARE

Chandan Guha, MBBS, PhD obtained his MBBS from the University of Calcutta, India and his PhD in Immunology at the Medical University of South Carolina, Charleston. Dr. Guha is currently a Professor, Vice Chairman and the Director of Translational Research of Radiation Oncology, at Montefiore Medical Center, Albert Einstein College of Medicine, NY. He is also a Professor of Pathology and Urology. Since the 1990s, Dr. Guha has been one of the early investigators to initiate research on the immunomodulation of radiation therapy, whereby irradiated tumors can act as autologous in situ tumor vaccines. He is the founding Director of the Einstein Institute for Onco-Physics, where principles of medical physics and imaging are being applied in the investigations of cancer biology and regenerative medicine. The Institute is spearheading research in radiation biology, therapeutic ultrasound and functional imaging by scientists and clinicians working together to translate bench-to-bedside research for designing novel clinical trials of combination of immunotherapy and cell therapies with radiation therapy and therapeutic ultrasound. Dr. Guha has also pioneered research on cell based regenerative therapies for mitigation and treatment of metabolic liver diseases and radiation injury.

Internationally, he is a visiting faculty of the Institute of Liver and Biliary Sciences, Delhi, India and the Shanghai Proton and Heavy Ion Center (SPHIC), Shanghai, China. As the First Director of Translational Oncology and Radiation Sciences at SPHIC, Dr Guha has been awarded an NCI-sponsored, BAA contract to conduct a randomized trial of Carbon ion therapy versus photon therapy for patients with locally advanced, unresectable pancreatic cancer. Dr. Guha has obtained multiple grants from the National Institutes of Health, Department of Defense, and the American Cancer Society. He has several patents, including the invention of an ultrasound device (SonoImmune®) for therapeutic in situ cancer vaccination.